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Calculate your patient’s disease activity using the interactive DAS28 calculator below.

The disease activity score in 28 joints (DAS28) is a composite, numerical score combining several discrete measures of RA activity into a single grading of disease severity. This measure is used in both trials and clinical practice and was developed because one single measure cannot adequately represent disease activity in RA.^1,2

EULAR recommendations on the management of early arthritis state that, in addition to structural damage and functional status, monitoring of disease activity should include the key components of the DAS28: tender and swollen joint count (TJC and SJC), erythrocyte sedimentation rate (ESR), C-reactive protein (CRP) level and patient’s global assessment of general health measured on a visual analogue scale (VAS). Arthritis activity should be assessed at 1–3 month intervals until remission is achieved.³

References

1. van der Heijde D, et al. Judging disease activity in clinical practice in rheumatoid arthritis. First step in the development of a “disease activity score”. Ann Rheum Dis 1990; 49:916–920.
2. Prevoo M, et al. Modified disease activity scores that include twenty-eight-joint counts. Development and validation in a prospective longitudinal study of patients with rheumatoid arthritis. Arthritis Rheum 1995; 38:44–48.
3. Combe B, et al. EULAR recommendations for the management of early arthritis: Report of a task force of the European Standing Committee for International Clinical Studies Including Therapeutics (ESCISIT). Ann Rheum Dis 2007; 66:34–45.